FAQs ADVATE Frequently Asked Questions
Where can I find information on insurance or factor assistance?
Visit www.thereforyou.com for information on insurance and factor assistance.
Where is ADVATE manufactured?
Baxter Healthcare Corporation, demonstrating its continued commitment to reinvest in supporting the hemophilia community, has established manufacturing capabilities for ADVATE [Antihemophilic Factor (Recombinant), Plasma/Albumin-Free Method] on two continents.2-4
The U.S. production site is located at Baxter’s Thousand Oaks, California facility, and complements the state-of-the-art manufacturing facility at Neuchâtel, Switzerland, which has produced ADVATE since its approval in 2003. The Thousand Oaks facility will continue to manufacture RECOMBINATE [Antihemophilic Factor (Recombinant)], the world’s first recombinant factor VIII treatment for hemophilia A.4,13
I have a clinical question about ADVATE.
Who can I contact?
Please contact Baxter Medical Information.
8:00 am - 5:00 pm (PST)
How can I contact a Baxter representative in my area?
Contact the ADVATE Hotline for general ADVATE [Antihemophilic Factor (Recombinant), Plasma/Albumin-Free Method] information, including reimbursement support and ordering educational material. Call 1-888-4-ADVATE (423-8283) 9am-11pm Eastern Standard Time.
Does ADVATE have a free trial program?
Yes. You may be eligible to receive six FREE doses of ADVATE by signing up for our Freedom of Choice program.
Please scroll down for ADVATE Indication and Detailed Important Risk Information.
Indication for ADVATE [Antihemophilic Factor (Recombinant), Plasma/Albumin-Free Method]
ADVATE [Antihemophilic Factor (Recombinant), Plasma/Albumin-Free Method] is a medicine used to replace clotting factor VIII that is missing in people with hemophilia A (also called “classic” hemophilia). ADVATE is used to prevent and control bleeding in adults and children (0-16 years) with hemophilia A. Your healthcare provider may give you ADVATE when you have surgery. ADVATE can reduce the number of bleeding episodes in adults and children (0-16 years) when used regularly (prophylaxis).
ADVATE is not used to treat von Willebrand Disease.
Detailed Important Risk Information for ADVATE
You should not use ADVATE if you are allergic to mice or hamsters or any ingredients in ADVATE.
You should tell your healthcare provider if you have or have had any medical problems, take any medicines, including prescription and non-prescription medicines and dietary supplements, have any allergies, including allergies to mice or hamsters, are nursing, are pregnant, or have been told that you have inhibitors to factor VIII.
You can have an allergic reaction to ADVATE. Call your healthcare provider right away and stop treatment if you get a rash or hives, itching, tightness of the throat, chest pain or tightness, difficulty breathing, lightheadedness, dizziness, nausea, or fainting.
Your body may form inhibitors to factor VIII. An inhibitor is part of the body’s normal defense system. If you form inhibitors, it may stop ADVATE from working properly. Consult with your healthcare provider to make sure you are carefully monitored with blood tests for the development of inhibitors to factor VIII.
Side effects that have been reported with ADVATE include: cough, sore throat, unusual taste, abdominal pain, diarrhea, nausea/vomiting, headache, fever, dizziness, hot flashes, chills, sweating, joint swelling/aching, itching, hematoma, swelling of legs, runny nose/congestion, and rash.
Call your healthcare provider right away about any side effects that bother you or if your bleeding does not stop after taking ADVATE.
Please see ADVATE full Prescribing Information.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.