Mike, father of 2 boys, 6 and 7, with hemophilia A
Spending quality time together as a family is important to the Neuberts—and so is staying on top of hemophilia care. Hear Mike and Heidi discuss the switch from on-demand to prophylactic treatment for their 2 boys with hemophilia A.
Trevor, 15 years old
As an actor and songwriter, Trevor has a busy schedule. See how he relies on prophylactic treatment to reduce his bleeds and continue to do what matters most to him.
Willie, 49 years old
For Willie, since he has tried prophylaxis, he has had fewer bleeds. He spends time going about his day with his family instead of worrying about having frequent bleeds. Hear about Willie’s passion for cooking and bringing everyone together around the dinner table.
Find a variety of quick links to ADVATE resources you can access on your own or with your patients. Baxter is committed to supporting your practice and your patients with hemophilia A.
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aIn a clinical study, after switching from 6 months of on-demand treatment to 12 months of prophylaxis with ADVATE in 53 previously treated patients with severe or moderately severe hemophilia A.

bA clinical study that evaluated treatment efficacy (the ability to control and reduce bleeds) of 2 prophylaxis regimens—every second day (standard) prophylaxis dosed at 20-40 IU/kg every 48 hours and every third day (pharmacokinetic-driven) prophylaxis dosed at 20-80 IU/kg every 72 hours, targeted to maintain factor VIII trough levels ≥1%.

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Proven Results

Prophylactic treatment with ADVATE has been shown to reduce bleeds in people with hemophilia A.1,a,b

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Clinically Meaningful Improvements* in Physical Health-Related Quality of Life1,3

See the clinical study results observed after 12 months of prophylactic treatment with ADVATE.

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Freedom of Choice Trial Program

You may be eligible for 6 free sample doses of ADVATE.

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8 Unique Video Stories

You can discover the journey of a few patients striving toward a goal of zero bleeds with prophylactic treatment with ADVATE.

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Find a Single-Vial Dose

ADVATE offers a broad selection of single vial dosing options.

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ADVATE’s History

10 Years of Commitment

View the Timeline

Mixing with BAXJECT II

BAXJECT II Needle-less Transfer device offers easy mixing.

Watch Demonstration Video

Unlocking Self-Potential

*Clinically meaningful changes were not seen in the physical health-related sub-categories of General Health and Physical Functioning and the mental health-related component score and sub-categories of Mental Health, Role Emotional, Social Functioning, and Vitality.1

Indication for ADVATE [Antihemophilic Factor (Recombinant), Plasma/Albumin-Free Method]

ADVATE [Antihemophilic Factor (Recombinant), Plasma/Albumin-Free Method] is a medicine used to replace clotting factor VIII that is missing in people with hemophilia A (also called “classic” hemophilia). ADVATE is used to prevent and control bleeding in adults and children (0-16 years) with hemophilia A. Your healthcare provider may give you ADVATE when you have surgery. ADVATE can reduce the number of bleeding episodes in adults and children (0-16 years) when used regularly (prophylaxis).

ADVATE is not used to treat von Willebrand Disease.

Detailed Important Risk Information for ADVATE

You should not use ADVATE if you are allergic to mice or hamsters or any ingredients in ADVATE.

You should tell your healthcare provider if you have or have had any medical problems, take any medicines, including prescription and nonprescription medicines and dietary supplements, have any allergies, including allergies to mice or hamsters, are nursing, are pregnant, or have been told that you have inhibitors to factor VIII.

You can have an allergic reaction to ADVATE. Call your healthcare provider right away and stop treatment if you get a rash or hives, itching, tightness of the throat, chest pain or tightness, difficulty breathing, lightheadedness, dizziness, nausea, or fainting.

Your body may form inhibitors to factor VIII. An inhibitor is part of the body’s normal defense system. If you form inhibitors, it may stop ADVATE from working properly. Consult with your healthcare provider to make sure you are carefully monitored with blood tests for the development of inhibitors to factor VIII.

Side effects that have been reported with ADVATE include: cough, sore throat, unusual taste, abdominal pain, diarrhea, nausea/vomiting, headache, fever, dizziness, hot flashes, chills, sweating, joint swelling/aching, itching, hematoma, swelling of legs, runny nose/congestion, and rash.

Call your healthcare provider right away about any side effects that bother you or if your bleeding does not stop after taking ADVATE.

Please see ADVATE full Prescribing Information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

USBS34130038

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Caregivers

Mike, father of 2 boys, 6 and 7, with hemophilia A
Spending quality time together as a family is important to the Neuberts—and so is staying on top of hemophilia care. Hear Mike and Heidi discuss the switch from on-demand to prophylactic treatment for their 2 boys with hemophilia A.

Teens &
Young Adults

Trevor, 15 years old
As an actor and songwriter, Trevor has a busy schedule. See how he relies on prophylactic treatment to reduce his bleeds and continue to do what matters most to him.

Adults

Willie, 49 years old
For Willie, since he has tried prophylaxis, he has had fewer bleeds. He spends time going about his day with his family instead of worrying about having frequent bleeds. Hear about Willie’s passion for cooking and bringing everyone together around the dinner table.

Healthcare Professionals

Find a variety of quick links to ADVATE resources you can access on your own or with your patients. Baxter is committed to supporting your practice and your patients with hemophilia A.