Ever wonder who made your ADVATE [Antihemophilic Factor (Recombinant)] and how? We went behind the scenes at one of our Shire manufacturing facilities to give you a look at how ADVATE is made.Watch the video
Ever wonder who made your ADVATE [Antihemophilic Factor (Recombinant)] and how? We went behind the scenes at one of our Shire manufacturing facilities to give you a look at how ADVATE is made.
The Shire CoPay Assistance Program offers financial assistance, insurance support, and a wealth of resources.
Watch patient story videos, connect with your local Shire Representative, find details on a local NHF Walk, and join in the fun with the Eco-Trek game for ADVATE.
The reconstitution process with the BAXJECT III system is easy, fast, and designed for you.1
FREEDOM OF CHOICE™ Free-Trial Program You may be eligible for 6 free trial doses of ADVATE.Find Out Now
Download Resources that Can Help You Stay on Track Downloadable PDF resources like the Goals Worksheet, Bleed Assessment Sheet, and ABR Worksheet can help you track your bleeds and see your results.Get Printable Resources
Unique Video Stories You can discover the journey of a few patients striving toward a goal of zero bleeds with prophylactic treatment with ADVATE.Watch Videos
Shire’s CoPay Program for ADVATE WE’VE GOT YOU COVERED. The Shire CoPay Assistance Program offers financial assistance, insurance support, and a wealth of resources.Find Help
See information about prophylaxis in adults and children.Learn More
See the clinical study results observed after 12 months of prophylactic treatment with ADVATE.Learn More
ADVATE offers a broad selection of single vial dosing options.Learn More
Shire is proud of its commitment to the hemophilia A community.View the Timeline
ADVATE is a medicine used to replace clotting factor (factor VIII or antihemophilic factor) that is missing in people with hemophilia A (also called "classic" hemophilia).
ADVATE is used to prevent and control bleeding in adults and children (0-16 years) with hemophilia A.
Your healthcare provider may give you ADVATE when you have surgery.
ADVATE can reduce the number of bleeding episodes in adults and children (0-16 years) when used regularly (prophylaxis).
ADVATE is not used to treat von Willebrand disease.
You should not use ADVATE if you:
Tell your healthcare provider if you are pregnant or breastfeeding because ADVATE may not be right for you.
You should tell your healthcare provider if you:
Your body may form inhibitors to factor VIII. An inhibitor is part of the body's normal defense system. If you form inhibitors, it may stop ADVATE from working properly. Consult with your healthcare provider to make sure you are carefully monitored with blood tests for the development of inhibitors to factor VIII.
You can have an allergic reaction to ADVATE.
Call your healthcare provider right away and stop treatment if you get a rash or hives, itching, tightness of the throat, chest pain or tightness, difficulty breathing, lightheadedness, dizziness, nausea or fainting.
Side effects that have been reported with ADVATE include: cough, headache, joint swelling/aching, sore throat, fever, itching, dizziness, hematoma, abdominal pain, hot flashes, swelling of legs, diarrhea, chills, runny nose/congestion, nausea/vomiting, sweating, and rash.
Tell your healthcare provider about any side effects that bother you or do not go away or if your bleeding does not stop after taking ADVATE.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
Click here for ADVATE full Prescribing Information.