In the hemophilia A community, no two patients are the same
When finding a treatment for hemophilia A, you and your healthcare provider should consider your individual needs.1 There are many characteristics that make you unique.1,2
While living with hemophilia A will always be a part of your reality—both the welcome and unwelcome moments—you need treatment options that can help navigate the complexities of real life with hemophilia A.
What is a bleeding phenotype?
A patient’s bleeding phenotype is a collection of his or her bleed history, including bleeding disorder type and severity, annual bleed frequency, and overall joint health.3
What is PK?
Pharmacokinetics (or “PK”) is the science of how a drug is used up in the body.4 A person's PK profile helps determine how quickly or slowly his or her body breaks down treatment. Each person’s PK profile is different, and treatment can be personalized to your profile.5
For adults and children with hemophilia A, ADVATE temporarily replaces the clotting factor VIII that's missing or low in the blood.6,7 In 2003, ADVATE became the first recombinant factor VIII treatment free of blood-based additives.7,8
What does recombinant mean?
Today, clotting factor VIII concentrates can be made without human plasma. These types of infusions are called recombinant clotting factors. Recombinant factor VIII was one of the first treatments approved for hemophilia that didn't pose the threat of transmitting a blood-borne virus.6
A legacy of real patient experience
Over 15 years of treatment experience in the real world.7
ADVATE is the most widely used factor VIII product globally, with over 33 billion International Units distributed.†8
†Based on units sold, as of February 2019.
ADVATE is indicated for prophylaxis, on-demand, and surgical use in children and adults.7
Selected Important Risk Information
Who should not use ADVATE?
Do not use ADVATE if you:
- Are allergic to mice or hamsters.
- Are allergic to any ingredients in ADVATE.
Tell your HCP if you are pregnant or breastfeeding because ADVATE may not be right for you.
Please see Detailed Important Risk Information below.
Interested in ADVATE?
A doctor discussion guide can help you have a productive conversation with your healthcare provider about your treatment options.
Committed to advancing hemophilia A care
Since introducing the first recombinant factor VIII treatment, Takeda has made advancements in dosing options, reconstitution with BAXJECT III®, and the introduction of myPKFiT® for personalized treatment.7,8